How to prepare for the prostate-specific antigen blood test

The PSA (prostate-specific antigen) blood test is an important tool used to screen for prostate abnormalities, including prostate cancer and benign prostatic hyperplasia (BPH). To ensure your results are as accurate as possible, it’s essential to follow a few simple preparation steps before your test.

1. Avoid Sexual Activity for 48 Hours

Ejaculation can cause a temporary spike in PSA levels, which may lead to a false reading.

Tip: Refrain from sexual activity, including masturbation, for at least 48 hours before your PSA test. This helps ensure that your results are not falsely elevated.

2. Dress for Easy Access

Your PSA blood sample will typically be taken from a vein in your arm.

Tip: Wear clothing with sleeves that can be easily rolled up to make the process faster and more comfortable.

3. Let Your Doctor Know About Recent Exams

If you've had certain urological procedures, such as a cystoscopy or a needle biopsy of the prostate, these can temporarily elevate PSA levels.

Tip: Inform your doctor if you've undergone either of these tests recently. You may need to reschedule your PSA test for a few weeks later to allow your PSA level to normalize.

4. Wait After a Urinary Tract Infection

A urinary tract infection (UTI) can also affect PSA readings. PSA testing should not be performed until several weeks after successful treatment of a UTI.

Tip: If you've recently completed treatment for a UTI, talk to your doctor about the best time to schedule your PSA test to avoid misleading results.

Bottom Line

Following these simple preparation tips can help ensure that your PSA blood test provides the most accurate and useful results. If you’re unsure about your timing or have had recent exams or infections, speak with your healthcare provider before testing.